Both the English and Javanese' languages describe music largely in metaphoric terms. In English, for instance, we use the spatial metaphor "up" and "down" to refer to differences in pitch. In Javanese these same differences are...
There are many and diverse methods available that can help researchers, designers, developers, and engineers integrate ethics in their research and innovation projects. In practice, however, they can find this challenging. They...
In Ecstasy of Reason, Jean-François Courtine states that F.W.J. Schelling’s late, “positive philosophy” is “not a sublime ground of being as a whole, but the contrary itself of a ground, the attempt of a phenomenology of … the...
Mindfulness training programmes have shown to encourage prosocial behaviours and reduce antisocial tendencies in adolescents. However, less is known about whether training affects susceptibility to prosocial and antisocial...
The aims of our study were to use whole genome sequencing in a cross-sectional cohort of patients to identify new variants in genes implicated in neuropathic pain, to determine the prevalence of known pathogenic variants and to...
Unruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target...
BACKGROUND AND AIMS: The prevalence of chronic liver disease in adults exceeds 30% in some countries and there is significant interest in developing tests and treatments to help control disease progression and reduce healthcare...
The smallest characteristic scales, at which electron dynamics determines the plasma behaviour, are the next frontier in space and astrophysical plasma research. The analysis of astrophysical processes at these scales lies at...
Mutations in fumarate hydratase (FH) cause hereditary leiomyomatosis and renal cell carcinoma1. Loss of FH in the kidney elicits several oncogenic signalling cascades through the accumulation of the oncometabolite fumarate2....
In contrast to mono- or biallelic loss of tumor-suppressor function, effects of discrete gene dysregulations, as caused by non-coding (epi)genome alterations, are poorly understood. Here, by perturbing the regulatory genome in...
We present a comprehensive analysis of the evolution of the morphological and structural properties of a large sample of galaxies at z = 3–9 using early James Webb Space Telescope (JWST) CEERS NIRCam observations. Our sample...
We report on the host properties of five X-ray-luminous active galactic nuclei (AGN) identified at 3 < z < 5 in the first epoch of imaging from the Cosmic Evolution Early Release Science Survey. Each galaxy has been imaged with...
BACKGROUND: Robot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies...
AbstractPredicting COVID-19 severity is difficult, and the biological pathways involved are not fully understood. To approach this problem, we measured 4701 circulating human protein abundances...